ups and downs

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They have their ups and downs while working.
他们在工作的时候也会高兴和低落。
Ask them about the ups and downs of their husband, and what compromises they may have had to make over the years.
问一些关于她们和丈夫的起起伏伏。比如，这么多年，他们之间有什么承诺啊；
The truth is that the organisation has had its ups and downs, which have largely coincided with support or hostility to it from the great powers.
事实是这一国际组织已几经沉浮，而它的沉浮在很大程度上取决于一些大国对它所采取的支持或敌对态度。

Jackson had ups and downs in his career, and faced unproven allegations that he had molested children.
A life, a fulfilling life, a rich life includes ups and downs, includes pain and getting up again, includes failure and getting up again.
生活，令人满意的生活，丰富的生活包括了起起落落，包括了痛苦和再次振作，包括了失败和再次奋斗。
哈佛公开课 - 幸福课课程节选
And you felt great probably for the rest of the senior year-- I mean, still ups and downs; but overall, high levels of happiness.
可能整个高三都会感觉很棒-,当然难免起起落落;,但总是来说是高水平的快乐。
哈佛公开课 - 幸福课课程节选

For many, it comes from families where there were a lot of ups and downs.
FORBES: The Hidden Work-Life Balance Crisis Among Entrepreneurs

If someone or something experiences ups and downs, a mixture of good and bad things happens to him, her, or it.

沉浮
Literary canon is continuous ups and downs in the maintenance of power, the contest and the decomposition.
文学经典便在权力的维护、争夺与分解之中不断沉浮。
历史学
盛衰
IWhy Zheng attached great importance to family education was because he was well known about the cause of those bureautical and landlord family’s ups and downs in the history.
一、曾国藩重视家庭教育，是因为他对历史上官僚地主家庭的盛衰看得很清楚。